Only time will tell if this hypothesis ends up in that same graveyard, or changes the way we think about lipoproteins and atherosclerosis.
Let’s start with what we know, then fill in the connections, with the goal of creating an eating strategy for those most interested in delaying the onset of cardiovascular disease.
The question this begs, of course, is which of these measurements is most predictive of risk?
Maybe it’s because I’m a math geek, but such models just seem intuitive to me because I think of most things in life in terms of calculus, especially integrals, the “area under a curve.” [I once tried to explain to a girlfriend who thought I wasn’t spending enough time with her that my interest in her should be thought of in terms of the area under the curve, rather than any single point in time.
That is, think in terms of the integral function, not the point-in-time function.
In that sense, the subjects in Group 3 can be viewed as the “control” for the U. population, and Group 1 can be viewed as an intervention group for what happens when you do nothing more in your diet than remove sugar, which was the first dietary intervention I made in 2009.
Despite the short duration of this study and the relatively small number of subjects (16 per group), the differences brought on by the interventions were significant.